Lion’s Mane (Hericium erinaceus)

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Borrelia

About Lion's Mane

Plant: Hericium erinaceus

A medicinal mushroom that stimulates Nerve Growth Factor production and accelerates myelination, specifically recommended by Buhner for cognitive repair and rebuilding damaged neuronal networks in chronic neuroborreliosis.

Reference dosing

Tincture dose — 1:53.13–6.25ml, 3–6 times daily
Tincture dose — 1:31.88–3.75ml, 3–6 times daily
Capsule dose (mg)625–1,250mg of dried herb, 3–6 times daily
Calculated from Buhner's tincture dose (1ml of a 1:5 tincture = 200mg of dried herb).

Buhner does not give a standard 1:5 dose for this herb — figures here are calculated from his 1:2 baseline instead of the usual 1:5 baseline.

Capsule whole-herb extracts vary by manufacturer (a concentrated extract needs less than a plain powder). Treat these figures as a guide only and follow the product label.

These are figures from the sources used on this site. They are not a prescription. Follow the product label and your prescriber.

Safety and cautions

Contraindications: Do not use if you are allergic to lion's mane or other mushrooms or moulds; severe allergic reactions are possible (stop and get help straight away if you get breathing problems, swelling, hives or fainting). Tell your doctor first if you have asthma or kidney or liver problems. Pregnancy and breastfeeding safety is not known (WebMD). Drug interactions are not fully understood, so check with a pharmacist before combining it with medicines. Always check with your prescriber or pharmacist, especially if you take blood thinners or other regular medicines.

Herbs can interact with prescription medicines and other supplements. Check with your prescriber or pharmacist first, and do not use herbs in pregnancy or while breastfeeding unless a doctor agrees.

Information last checked: 6 November 2026.

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